Structural and molecular bioinformatics enables the analysis and modeling of protein three-dimensional structures to better understand their biological functions and interactions.
In microbiology, it is applied to 16S rRNA sequence analysis for phylogenetic tree construction and microorganism identification.
In health sciences, molecular docking is used to predict protein–ligand interactions, identify therapeutic targets, and support drug discovery and development
Metagenomics accesses microbial genes directly from environmental DNA via 16S rRNA profiling and enzyme identification from uncultured organisms in extreme niches (e.g., salt lakes). Algeria’s ecological diversity fuels high-throughput sequencing and bioinformatics for biodiversity and evolutionary analysis. The Metagenomics and Biomathematics team develops databases, platforms, and valorization tools for economic applications, including soil fauna responses to abiotic stresses.
The Applied and Molecular Microbiology team provides biological systems as alternatives to conventional chemical processes through green (food/agro), yellow (environmental bioremediation), and red (health/pharma) biotechnologies. It isolates and optimizes microorganisms producing industrial biomolecules (metabolites, enzymes, biosurfactants) for agriculture, feed, food, and therapy, with expertise in genomics, fermentation, biocorrosion, and biofilms. Objectives include valorizing Algerian genetic resources for depolluting industrial wastes, remediating contaminated sites, studying effects on metal oxides, and protein crystallization.
Antioxidant biomolecules from plant and lichen secondary metabolites target oxidative stress central to diabetes, atherosclerosis, and neurodegenerative disorders. This project valorizes plant resources, a scientific treasure to safeguard, through targeted ethnobotany, high-throughput extractions, and qualitative/quantitative phytochemical analyses. Innovative biochemical and histological approaches assess the protective effects of these extracts on cellular redox balance and molecular/structural integrity.
Thin films of metal oxides (NiO, TiO₂, etc.) captivate due to their chemical, electrical, and optical properties, ideal for environmental remediation and antibacterial materials (medical devices, hospital textiles, food packaging). The objective optimizes deposition parameters to enhance photocatalytic and antimicrobial effects for industrial applications, valorizing chemical/organic resources. Studies reveal structural, morphological, optical, and biological properties via: film elaboration, thermal treatment, physico-chemical/spectral characterizations, and in vitro tests.
Classical technologies and biotechnologies have greatly improved productivity in animal sciences, particularly in nutrition, reproduction, and health.
Nutritional biotechnologies use microorganisms and fermentation processes to produce nutrients, improve feed digestibility, and reduce environmental pollution.
In animal reproduction, artificial insemination combined with cryopreservation enhances genetic improvement and productivity.
In health and livestock management, molecular biology tools, disease diagnosis, and management software ensure performance, quality, and traceability of animal products.